{"id":288,"date":"2022-01-12T11:38:49","date_gmt":"2022-01-12T03:38:49","guid":{"rendered":"\/?post_type=news&p=288"},"modified":"2022-06-28T10:22:45","modified_gmt":"2022-06-28T02:22:45","slug":"%e5%8a%a9%e5%8a%9b%e7%99%8c%e7%97%87%e8%af%8a%e7%96%97%e6%97%a9%e7%ad%9b%e6%97%a9%e6%b2%bb%e6%99%ba%e6%a0%b8%e7%94%9f%e7%89%a9%e5%bc%95%e5%85%a5%e9%9d%a9%e6%96%b0%e6%80%a7her-2","status":"publish","type":"news","link":"https:\/\/www.smartnucl.com\/archives\/news\/%e5%8a%a9%e5%8a%9b%e7%99%8c%e7%97%87%e8%af%8a%e7%96%97%e6%97%a9%e7%ad%9b%e6%97%a9%e6%b2%bb%e6%99%ba%e6%a0%b8%e7%94%9f%e7%89%a9%e5%bc%95%e5%85%a5%e9%9d%a9%e6%96%b0%e6%80%a7her-2","title":{"rendered":"\u52a9\u529b\u764c\u75c7\u8bca\u7597\u65e9\u7b5b\u65e9\u6cbb\u667a\u6838\u751f\u7269\u5f15\u5165\u201c\u9769\u65b0\u6027\u201dHer-2\u9776\u70b9\u653e\u5c04\u6027\u663e\u50cf\u836f\u7269"},"content":{"rendered":"<p><span id=\"profileBt\" class=\"rich_media_meta rich_media_meta_nickname\"><a id=\"js_name\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\"><\/a><a href=\"https:\/\/mp.weixin.qq.com\/s\/bHZAn94ccJTkSfE8b5nZuA\"><em><span style=\"color: #0000ff;\">\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e08 <\/span><\/em><\/a><\/span><span style=\"color: #0000ff;\"><em class=\"rich_media_meta rich_media_meta_text\"> 2022-01-12 22:08<\/em><\/span><\/p>\n<p>\u764c\u75c7\u6b63\u6301\u7eed\u5411\u4eba\u7c7b\u53d1\u8d77\u6311\u6218\u3002<\/p>\n<p>\u636e\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u56fd\u9645\u764c\u75c7\u7814\u7a76\u673a\u6784\uff08 IARC \uff09\u53d1\u5e03\u7684\u5168\u7403\u6700\u65b0\u764c\u75c7\u6570\u636e\u663e\u793a\uff0c2020 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Tolmachev\u548cSophia Hober\u5171\u540c\u5f00\u53d1\uff0c\u4ece\u7814\u53d1\u4f18\u5316\u81f3\u4eca\u5df2\u6709\u6570\u5341\u4f59\u5e74\uff0c\u76f8\u5173\u7814\u7a76\u5df2\u53d1\u886830\u591a\u7bc7\u9ad8\u6c34\u5e73SCI\u6587\u732e\u3002\u76ee\u524d\u8be5\u836f\u7269\u5df2\u5b8c\u6210\u4e34\u5e8aI\u671f\u8bd5\u9a8c\uff0c\u5bf9\u4e8e\u672a\u7ecf\u6cbb\u7597\u7684\u539f\u53d1\u6027\u4e73\u817a\u764c\u60a3\u8005\uff0c\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c ADAPT6\u5b89\u5168\u6027\u597d\uff0c\u65e0\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\uff0c\u6ce8\u5c04\u540e2h\u5185\u5373\u53ef\u5feb\u901f\u5206\u8fa8Her-2(+)\u548cHer-2(-)\u80bf\u7624\u3002<\/p>\n<figure id=\"attachment_290\" aria-describedby=\"caption-attachment-290\" style=\"width: 865px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" class=\"wp-image-290 size-full\" src=\"\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e082.png\" alt=\"\" width=\"865\" height=\"433\" srcset=\"https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e082.png 865w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e082-300x150.png 300w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e082-768x384.png 768w\" sizes=\"(max-width: 865px) 100vw, 865px\" \/><figcaption id=\"caption-attachment-290\" class=\"wp-caption-text\">\u4ece\u5de6\u81f3\u53f3\u4f9d\u6b21\uff1aADAPT6\u5206\u5b50\u7ed3\u6784\u3001\u6ce8\u5c04ADAPT6 2h\u540e\u80bf\u7624\/\u5bf9\u4fa7\u4e73\u817a\u6bd4\u503c\u3001\u6ce8\u5c04ADAPT6 2h\u540e\u5168\u8eab\u663e\u50cf<\/figcaption><\/figure>\n<p>\u9664\u80fd\u5e94\u7528\u4e8e\u4e73\u817a\u764c\u3001\u80c3\u764c\u8bca\u7597\u5916\uff0cHer-2\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53ca\u8180\u80f1\u764c\u8bca\u7597\u9886\u57df\u7684\u4ef7\u503c\u4e5f\u5728\u9010\u6e10\u88ab\u53d1\u73b0\u3002\u672a\u6765ADAPT6\u65e0\u7591\u4e5f\u5c06\u901a\u8fc7\u5206\u5b50\u663e\u50cf\u65b9\u5f0f\uff0c\u5b9e\u73b0\u76f8\u5173\u764c\u79cd\u7684\u65e9\u7b5b\u65e9\u6cbb\u3002<\/p>\n<p>\u5b9e\u9645\u4e0a\uff0c\u5728\u5f15\u5165ADAPT6\u7684\u540c\u65f6\uff0c\u667a\u6838\u751f\u7269\u81ea\u7814\u7684\u653e\u5c04\u6027\u663e\u50cf\u836f\u7269\u4e5f\u5728\u5feb\u901f\u63a8\u8fdb\u5f53\u4e2d\u3002\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u4e86\u653e\u5c04\u6027\u540c\u4f4d\u7d20<sup>68<\/sup>Ga\u6807\u8bb0\u7684PD-L1\u8868\u8fbe\u663e\u50cf\u5242\uff08SNA002\uff09\u548c\u5168\u8eab\u80bf\u7624\u6d78\u6da6\u6dcb\u5df4\u7ec6\u80de\uff08TIL\uff09\u663e\u50cf\u5242(SNA006)\uff0c\u4e24\u6b3e\u663e\u50cf\u5242\u5747\u5177\u6709\u4e0eADAPT6\u76f8\u4f3c\u7684\u4f18\u52bf\uff0c\u5bf9\u4e34\u5e8a\u4e0a\u80bf\u7624\u514d\u75ab\u7528\u836f\u5177\u6709\u6781\u5927\u6307\u5bfc\u4f5c\u7528\u548c\u5f00\u53d1\u4ef7\u503c\u3002<\/p>\n<p>\u636e\u987b\u6d9b\u535a\u58eb\u900f\u9732\uff0cSNA002\u5373\u5c06\u5728\u4e2d\u7f8e\u4e24\u56fd\u540c\u65f6\u5f00\u542fIND\uff08\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff09\uff0c\u6709\u671b\u6210\u4e3a\u8fd110\u5e74\u6765\uff0c\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u7f8e\u56fd\u5f00\u5c55\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\u7684\u9996\u4e2a\u653e\u5c04\u6027\u8bca\u65ad\u836f\u7269\u3002\u9664\u6b64\u4ee5\u5916\uff0c\u667a\u6838\u751f\u7269\u4e5f\u5df2\u4e0e\u82cf\u5dde\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u5f00\u542f\u5408\u4f5c\uff0c\u56f4\u7ed5SNA006\u5f00\u5c55\u7814\u7a76\u8005\u53d1\u8d77\u7684\u4e34\u5e8a\u5b9e\u9a8c\u3002<\/p>\n<p><strong>\u6838\u533b\u5b66\u521b\u65b0\u836f\u54c1\u5e26\u6765\u764c\u75c7\u6cbb\u7597\u65b0\u5e0c\u671b<\/strong><\/p>\n<p>\u5728\u6301\u7eed\u6df1\u8015\u653e\u5c04\u6027\u663e\u50cf\u836f\u7269\u4ee5\u6ee1\u8db3\u80bf\u7624\u65e9\u7b5b\u65e9\u6cbb\u9700\u6c42\u7684\u540c\u65f6\uff0c\u667a\u6838\u751f\u7269\u4e5f\u5c06\u76ee\u5149\u805a\u7126\u5728\u80bf\u7624\u653e\u5c04\u6027\u6cbb\u7597\u836f\u7269\u65b9\u9762\u3002<\/p>\n<p>\u201c\u6211\u4eec\u60f3\u7528\u6700\u5177\u521b\u65b0\u6027\u7684\u6838\u533b\u5b66\u8bca\u7597\u4ea7\u54c1\uff0c\u7ed9\u60a3\u8005\u5e26\u6765\u65b0\u7684\u5e0c\u671b\u201d\u3002\u8c08\u53ca\u667a\u6838\u751f\u7269\u7684\u4f7f\u547d\uff0c\u987b\u6d9b\u535a\u58eb\u8868\u793a\uff0c\u76ee\u524d\uff0c\u667a\u6838\u751f\u7269\u5df2\u642d\u5efa\u4e86\u4e00\u7cfb\u5217\u6838\u533b\u5b66\u6cbb\u7597\u836f\u7269\u7684\u7814\u53d1\u7ba1\u7ebf\uff0c\u5728\u7cbe\u51c6\u8bca\u65ad\u4e4b\u540e\u63d0\u4f9b\u66f4\u52a0\u6709\u6548\u7684\u653e\u5c04\u6027\u6cbb\u7597\u836f\u7269\u3002<\/p>\n<p>\u5728\u4e1a\u5185\u4eba\u58eb\u770b\u6765\uff0c\u653e\u5c04\u6027\u6cbb\u7597\u836f\u7269\u53ef\u901a\u8fc7\u4f7f\u7528\u4f18\u5316\u7684\u8f7d\u4f53\u643a\u5e26\u653e\u5c04\u6027\u6838\u7d20\u5230\u8fbe\u80bf\u7624\u7ec4\u7ec7\uff0c\u5bf9\u80bf\u7624\u7ec4\u7ec7\u8fdb\u884c\u9009\u62e9\u6027\u8f90\u5c04\uff0c\u5bf9\u5468\u56f4\u5065\u5eb7\u7ec4\u7ec7\u4ea7\u751f\u6700\u5c0f\u6bd2\u6027\uff0c\u4ece\u800c\u5b9e\u73b0\u7cbe\u51c6\u9776\u5411\u6cbb\u7597\u80bf\u7624\u76ee\u7684\u3002\u6b64\u5916\uff0c\u5bf9\u4e8e\u56e0\u5176\u4ed6\u6cbb\u7597\u65b9\u5f0f\u5bfc\u81f4\u7684\u80bf\u7624\u8010\u836f\u95ee\u9898\uff0c\u653e\u5c04\u6027\u6cbb\u7597\u836f\u7269\u4ecd\u65e7\u80fd\u6709\u6548\u53d1\u6325\u6740\u4f24\u4f5c\u7528\uff0c\u7ed9\u60a3\u8005\u5e26\u6765\u66f4\u591a\u7684\u6cbb\u7597\u5e0c\u671b\u3002<\/p>\n<p>\u6b63\u662f\u57fa\u4e8e\u8fd9\u6837\u7684\u4f18\u52bf\uff0c\u8bfa\u534e\u3001\u62dc\u8033\u7b49\u8de8\u56fd\u836f\u4f01\u5df2\u5728\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\u3001\u524d\u5217\u817a\u764c\u7b49\u9886\u57df\u5e03\u5c40\u653e\u5c04\u6027\u6cbb\u7597\u836f\u7269\u3002\u667a\u6838\u751f\u7269\u4e5f\u5b8c\u6210\u4e86\u76f8\u5173\u9886\u57df\u7684\u591a\u6761\u7814\u53d1\u7ba1\u7ebf\u5e03\u5c40\u3002<\/p>\n<figure id=\"attachment_291\" aria-describedby=\"caption-attachment-291\" style=\"width: 518px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" class=\"wp-image-291 size-full\" src=\"\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e083.jpg\" alt=\"\" width=\"518\" height=\"271\" srcset=\"https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e083.jpg 518w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e083-300x157.jpg 300w\" sizes=\"(max-width: 518px) 100vw, 518px\" \/><figcaption id=\"caption-attachment-291\" class=\"wp-caption-text\">\u667a\u6838\u751f\u7269\u4ea7\u54c1\u7ba1\u7ebf<\/figcaption><\/figure>\n<p>\u5728\u8fd9\u4e00\u8fc7\u7a0b\u4e2d\uff0c\u667a\u6838\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u6280\u672f\u5e73\u53f0\u4e5f\u5728\u65e5\u81fb\u5b8c\u5584\u3002\u76ee\u524d\u516c\u53f8\u5df2\u5efa\u7acbSmart Sdbc\u3001SmartApa\u3001SmartRel\u4e09\u5927\u6280\u672f\u5e73\u53f0\uff0c\u5b9e\u73b0\u4e86\u653e\u5c04\u6027\u540c\u4f4d\u7d20\u4e0e\u7eb3\u7c73\u6297\u4f53\u7684\u5b8c\u7f8e\u878d\u5408\uff0c\u540c\u65f6\u907f\u514d\u7eb3\u7c73\u6297\u4f53\u81ea\u8eab\u7684\u80be\u4ee3\u8c22\u5f0a\u7aef\uff1b\u5e76\u5145\u5206\u5229\u7528\u7eb3\u7c73\u6297\u4f53\u5206\u5b50\u91cf\u5c0f\u3001\u7a7f\u900f\u80fd\u529b\u5f3a\u7b49\u7279\u70b9\uff0c\u6784\u5efa\u4e86\u4e00\u7cfb\u5217\u5177\u6709\u4f18\u5f02\u7597\u6548\u7684\u653e\u5c04\u6027\u8bca\u7597\u836f\u7269\u3002\u987b\u6d9b\u535a\u58eb\u4e5f\u900f\u9732\uff0c\u540e\u7eed\u516c\u53f8\u5c06\u5229\u7528\u4e0a\u8ff0\u6280\u672f\u5e73\u53f0\uff0c\u6301\u7eed\u5f00\u53d1\u6210\u719f\u80bf\u7624\u9776\u70b9\u7684\u653e\u5c04\u6027\u6cbb\u7597\u6027\u836f\u7269\uff0c\u5168\u9762\u52a0\u901f\u7814\u53d1\u8fdb\u7a0b\uff0c\u5f62\u6210\u6279\u91cf\u4ea7\u51fa\u3002<\/p>\n<figure id=\"attachment_292\" aria-describedby=\"caption-attachment-292\" style=\"width: 865px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" class=\"wp-image-292 size-full\" src=\"\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e084.png\" alt=\"\" width=\"865\" height=\"427\" srcset=\"https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e084.png 865w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e084-300x148.png 300w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e084-768x379.png 768w\" sizes=\"(max-width: 865px) 100vw, 865px\" \/><figcaption id=\"caption-attachment-292\" class=\"wp-caption-text\">\u667a\u6838\u751f\u7269Smart SDBC\u3001SmartPaa\uff0cSmartRel\u4e09\u5927\u6280\u672f\u5e73\u53f0<\/figcaption><\/figure>\n<p>\u201c\u4e2d\u56fd\u521b\u65b0\u653e\u5c04\u6027\u836f\u7269\u7531\u4e8e\u6280\u672f\u58c1\u5792\u95ee\u9898\u8fd110\u5e74\u6765\u53d1\u5c55\u7f13\u6162\uff0c\u4ec5\u6709\u6781\u5c11\u6570\u7684\u653e\u5c04\u6027\u8bca\u65ad\u836f\u7269\u8fdb\u5165\u4e34\u5e8a\uff0c\u800c\u653e\u5c04\u6027\u6cbb\u7597\u6027\u836f\u7269\u7814\u7a76\u9886\u57df\u51e0\u4e4e\u7a7a\u767d\u3002\u8fd1\u4e24\u5e74\u56fd\u9645\u653e\u5c04\u6027\u836f\u7269\u7814\u53d1\u9886\u57df\u65b9\u5174\u672a\u827e\uff0c\u4e2d\u56fd\u867d\u548c\u6b27\u7f8e\u76f8\u6bd4\u6709\u8f83\u660e\u663e\u7684\u5dee\u8ddd\uff0c\u4f46\u7531\u4e8e\u76f8\u5173\u9886\u57df\u7684\u7814\u53d1\u5747\u5904\u4e8e\u8f83\u65e9\u9636\u6bb5\uff0c\u6211\u4eec\u5177\u5907\u540e\u53d1\u4f18\u52bf\uff0c\u4ecd\u6709\u8fce\u5934\u8d76\u4e0a\u7684\u53ef\u80fd\u3002\u201d\u987b\u6d9b\u535a\u58eb\u8868\u793a\u3002<\/p>\n<p>\u53e6\u4ecb\u7ecd\uff0c\u667a\u6838\u751f\u7269\u8fd11\u4e07\u5e73\u65b9\u7c73\u7684\u5076\u8054\u3001\u653e\u5c04\u6027GMP\u8f66\u95f4\u6b63\u5728\u5efa\u8bbe\u5f53\u4e2d\uff0c\u9884\u8ba1\u57282022\u5e74\u5e95\u5373\u53ef\u4ea4\u4ed8\u4f7f\u7528\uff1b\u540c\u65f6\u516c\u53f8\u4e13\u4e1a\u5316\u9500\u552e\u56e2\u961f\u4e5f\u5c06\u4e8e2022\u5e74\u642d\u5efa\u5b8c\u6210\uff0c\u4e3a\u667a\u6838\u7b2c\u4e00\u4e2a\u6838\u533b\u5b66\u8bca\u7597\u4ea7\u54c1SNA001\u4e0a\u5e02\u505a\u597d\u51c6\u5907\u3002\u76f8\u5173\u5de5\u4f5c\u4e5f\u5c06\u52a9\u529b\u667a\u6838\u751f\u7269\u6700\u7ec8\u5b9e\u73b0\u81ea\u4e3b\u7814\u53d1\u751f\u4ea7\u5230\u9500\u552e\u7684\u5168\u6d41\u7a0b\u8986\u76d6\uff0c\u5b8c\u6210\u4ece\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u8f6c\u53d8\u3002<\/p>\n<p><strong>\u5173\u4e8e\u745e\u5178Hober biotech\u516c\u53f8<\/strong><\/p>\n<p>\u745e\u5178Hober biotech\u516c\u53f8\u6210\u7acb\u4e8e2020\u5e74\uff0c\u8054\u5408\u521b\u59cb\u4ebaVladimir Tolmachev\u548cSophia 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\/>\n<\/strong><\/p>\n<p><strong>\u6b22\u8fce\u8f6c\u53d1\u3001\u6b22\u8fce\u8f6c\u8f7d<\/strong><\/p>\n<p><strong>\u6b22\u8fce\u5173\u6ce8<\/strong><\/p>\n<p><strong>\u300a\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u6838\u533b\u5b66\u533b\u5e08\u5206\u4f1a\u5b98\u65b9\u7f51\u300b<\/strong><\/p>\n<p><strong>http:\/\/www.caonmp.com\/<\/strong><\/p>\n<p><img loading=\"lazy\" class=\"alignnone size-full wp-image-293\" src=\"\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e085.jpg\" alt=\"\" width=\"300\" height=\"315\" srcset=\"https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e085.jpg 300w, https:\/\/www.smartnucl.com\/wp-content\/uploads\/2022\/05\/\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e085-286x300.jpg 286w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u56fd\u6838\u533b\u5b66\u533b\u5e08 2022-01-12 22:08 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